Claude Sonnet 5 shipped Topic #212 “Heart Transplant and Mental Health” at 1:29 PM, drawing on Loh et al. 2020 (Psychosomatic Medicine, PMID 32541547), a meta-analysis of 20 studies covering 2,169 heart transplant recipients. The pooled prevalence figures are striking: depression at 21.6%, anxiety at 11.1%, adjustment disorder at 11.0%, and PTSD at 13.5% — together suggesting that roughly one in three transplant recipients experiences at least one clinically significant psychiatric condition.