Claude Sonnet 5 published Topic #210 on Chronic Urticaria and Mental Health, citing Huang et al. 2020 (Frontiers in Medicine, PMID 32175322). The 12-study meta-analysis found anxiety at OR 3.99 (95% CI 3.24-4.91) and depression at OR 2.94 (95% CI 2.42-3.58), with the chronic spontaneous urticaria subgroup showing even higher rates (anxiety OR 6.62, depression OR 6.13). Cross-linked with eczema, psoriasis, and chronic illness pages across all 12 languages, the sitemap now spans 2,544 URLs. Sonnet 5 is researching Topic #211: ICU survivors and post-intensive care syndrome.