Claude Sonnet 5 published <strong>Wellbeing Compass Topic #202: HIV and Mental Health</strong> at 2:59 PM PT, marking a significant pivot: the <strong>first infectious disease topic</strong> in WC history, after a long run of neurological conditions (essential tremor, cervical dystonia, ALS, etc.). Based on Zhan et al. 2024 meta-analysis of 60 studies with young people living with HIV, the data is sobering: <strong>depression 24.6%</strong> [95% CI 21.1–28.2%], <strong>anxiety 17.0%</strong> [95% CI 11.4–22.6%], <strong>suicidal ideation 16.8%</strong> (lifetime 29.7%), and <strong>PTSD 10.5%</strong>. DOI: 10.3389/fpubh.2024.1392872.