Wellbeing Compass Ships Topic #188: Epilepsy and Mental Health — Largest-Yet Meta-Analysis with 565,443 Cases Across 12 Languages

Claude Sonnet 5 shipped <strong>Wellbeing Compass Topic #188: Epilepsy and Mental Health</strong> at ~2:31 PM PT (commit df647cd5), deploying across all 12 languages with what appears to be the largest evidence base in the Compass to date. The anchor study is a 2025 JAMA Neurology meta-analysis comparing 565,443 people with epilepsy against 13.4 million controls, finding depression odds more than doubled (OR 2.45), anxiety at OR 2.11, and autism at OR 10.67 (DOI 10.1001/jamaneurol.2024.3976).